China TCM (Guilin) Industrial Park - Production Base

Integrated EPC for High-Capacity TCM Formula Granules & Decoction Piece Workshops

Scale:  60,000 sqm

Project Overview

A Regional Powerhouse for Comprehensive TCM Manufacturing

Engineering a high-performance facility optimized for multi-line extraction and advanced pharmaceutical preparation.

AIPURE delivered the full-professional cleanroom renovation and mechanical/electrical (M&E) installation for the formula granule and premium decoction piece workshops at the China TCM Guilin Industrial Park. The infrastructure supports an extensive production matrix, including 6 decoction piece lines, 3 extraction lines, and 4 granule preparation lines. Upon full operation, the base is designed to produce 2,000 tons of decoction pieces and 500 tons of granules (equivalent to 500 million bags) annually, with a projected output value exceeding 1 billion RMB.

Technical Highlights

  • Multi-Line Strategic Layout: Master planning for 13 simultaneous production lines to maximize workflow efficiency while eliminating cross-contamination risks.

  • Advanced Dust & Particle Control: Implementation of high-efficiency air purification systems specifically designed to manage the heavy dust loads typical of TCM processing.

  • Precision Environmental Stability: Automated regulation of temperature, humidity, and pressure gradients to meet the rigorous extraction and preparation requirements.

  • High-Volume Extraction Support: Infrastructure engineered to sustain an annual extraction capacity of 2,000 tons with consistent GxP compliance.

Engineering Challenges & Solutions

  • Synergy of Diverse Production Streams: Managing multiple production lines required a sophisticated spatial strategy. We scientifically partitioned the cleanroom zones and optimized the logistical flow to ensure that granule preparation and decoction piece processing operate in parallel without interference.

  • High-Efficiency Dust Containment: TCM manufacturing is inherently prone to dust generation. We deployed specialized filtration and airflow capture technologies to maintain superior air cleanliness, ensuring the facility adheres to strict pharmaceutical manufacturing standards.

  • Rigorous Parameter Regulation: The stability of the production environment is critical for drug quality. We implemented an automated environmental control system that provides real-time monitoring and adjustment of pressure gradients and thermal parameters across all preparation zones.

  • Standardized Full-Lifecycle Execution: To ensure a smooth transition to production, we followed a rigid quality control protocol throughout the installation of M&E systems and purification fit-outs, followed by comprehensive system commissioning to guarantee full compliance with industry regulations.

Construction Content

  • Decoction & Granule Preparation Suites: High-standard cleanroom environments for diverse TCM dosage forms.

  • Automated Extraction Modules: Specialized zones featuring integrated utility piping and thermal management.

  • High-Efficiency Air Handling Systems: Specialized HVAC infrastructure designed for superior dust and microbial control.

  • Integrated Power & Utility Distribution: Full-scale electrical and clean utility installation optimized for high-volume manufacturing.

Why This Project Defines AIPURE

“Mastering the complexity of high-volume, multi-line pharmaceutical manufacturing.”

The China TCM Guilin project showcases AIPURE’s mastery in “Complex Process Integration”. By delivering a massive facility that harmonizes 13 production lines with 100% compliance, we prove that our engineering solutions can handle the most intensive production targets while maintaining stable, fully classified non-sterile OSD manufacturing environments (ISO 14644-1 Class 8 / EU GMP Grade D).

Project Conclusion

The high-standard delivery of the Guilin Industrial Park has provided China TCM with an audit-ready, high-capacity manufacturing base. All systems, from dust control to environmental regulation, are operating stably, enabling the client to scale their production to 500 million bags annually. At AIPURE, we don’t just build cleanrooms; we build the high-output, compliant foundations that empower pharmaceutical giants to lead the regional market.

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Related Service

Cleanroom Consulting

Cleanroom Design

Construction

Product Manufacturing

Commissioning

Operation & Maintain

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