Bangqi Pharmaceutical — Multi-Phase Solid Dosage Manufacturing Complex
Full-Scale EPC for Multi-Phase Cleanroom Expansion & GMP Compliance
Scale: Total 15,000+ sqm (Phases I, II, III & IV)
Project Overview
A Versatile Hub for Traditional and Modern Pharmaceutical Formulations
Engineering a multi-functional production complex for liquid medicinal wines, aqueous extraction, and solid dosage forms.
AIPURE delivered the full-professional M&E (Mechanical, Electrical, and Plumbing) and purification infrastructure for this 20,000 sqm facility. The project serves as a critical production base for granule preparations, integrating three distinct manufacturing units: a Medicinal Wine workshop, an Aqueous Extraction workshop, and a Solid Dosage workshop. Our scope covered the complete installation of HVAC, process piping, electrical systems, and automated controls, ensuring a GxP-compliant environment for complex pharmaceutical processes.
Technical Highlights
Diverse Process Compatibility: Successful integration of explosive-proof ventilation (for medicinal wine), moisture-intensive extraction zones, and high-precision solid dosage suites.
Granulation-Specific Environmental Control: Advanced airflow and dust containment systems optimized for the crushing, mixing, granulation, and drying stages.
Full-Professional M&E Integration: One-stop delivery of HVAC, specialized piping, power distribution, and intelligent automation systems.
GMP-Certified Excellence: High-standard hardware implementation that facilitated the successful completion of the National GMP certification.
Engineering Challenges & Solutions
Managing Divergent Environmental Standards: Combining medicinal wine (ethanol-based), aqueous extraction (heat/moisture-intensive), and solid dosage lines within a single 20,000 sqm complex required a sophisticated zonal strategy. We engineered independent ventilation and explosive-proof systems for the wine unit while designing specialized moisture-removal protocols for the extraction zone, preventing any cross-interference.
Dust & Humidity Control for Granule Lines: Granule production involves high dust-generating processes like crushing and granulation. We designed a high-efficiency HVAC system with optimized air distribution to ensure total dust containment and precise humidity stability, protecting product integrity and operator safety.
Multidisciplinary Coordination in Confined Spaces: Managing the intersection of HVAC, process piping, and electrical systems across multiple workshops required elite project management. We utilized a unified construction model to synchronize overlapping workfronts, ensuring all utility lines were routed logically to maximize operational space and maintenance access.
Absolute Precision in Pressure Gradients: To prevent cross-contamination between different dosage forms, we established a rigorous pressure gradient control system. This ensures that airflow remains unidirectional from high-cleanliness zones to lower-level areas, even during simultaneous multi-line production.
Construction Content
Solid Dosage & Granulation Suites: High-standard cleanrooms with integrated dust collection and environmental regulation.
Medicinal Wine & Extraction Modules: Specialized workshops featuring explosive-proof infrastructure and advanced moisture management.
Full M&E Utility Infrastructure: Total installation of clean utility piping, HVAC air handling units, and power distribution networks.
Automated Control Systems (BMS): Centralized digital infrastructure for real-time monitoring of temperature, humidity, and pressure gradients.
Why This Project Defines AIPURE
“Mastering the complexity of multi-form pharmaceutical environments.”
The Granule Preparation Base project highlights AIPURE’s ability to manage “Multi-Process Integration.” By delivering a facility that harmonizes flammable liquid handling with sensitive solid-dosage cleanrooms, we prove that our engineering solutions can adapt to the most diverse and demanding pharmaceutical production requirements.
Project Conclusion
The successful high-standard delivery of this manufacturing base has provided our client with a secure, versatile environment for large-scale granule production. All professional systems were installed successfully against the documented acceptance criteria, meeting all technical benchmarks for GxP compliance. At AIPURE, we don’t just build cleanrooms; we build the flexible, high-performance infrastructure that allows pharmaceutical leaders to manage diverse product portfolios with confidence.
VIEW MORE PROJECTS
Related Service
Cleanroom Consulting
Cleanroom Design
Construction
Product Manufacturing
Commissioning
Operation & Maintain
Contact Information
Global Sales & Technical Support
+86 15607108630
WhatsApp Support
+86 15607108630
China Headquarter Address
No 18 Finance Harbor 4th Road, Wuhan, China.
Request a Tailored Proposal
We respond to technical inquiries within 24 hours.
