Shanghai Hicon Pharm (Hubei) — Large-Scale API Manufacturing Base
Full EPC General Contracting for API Infrastructure & Cleanroom Systems
Scale: 40,000 sqm
Project Overview
A Comprehensive Landmark for Integrated API Manufacturing
Engineering a massive industrial complex for high-capacity chemical Active Pharmaceutical Ingredient (API) production.
AIPURE served as the EPC (Engineering, Procurement, and Construction) general contractor for this extensive 40,000 sqm facility for Huilen Pharma. The project represents a full-spectrum industrial delivery, encompassing chemical API workshops, advanced R&D laboratories, and a complete suite of support infrastructure. From mechanical installations and cleanroom renovation to complex outdoor tank farms and utility pipe racks, this project solidifies Huilen Pharma’s production capacity of over 20 tons of APIs annually.
Technical Highlights
Total EPC Lifecycle Management: Seamless integration of design, procurement, and construction across multiple engineering disciplines.
Massive Infrastructure Scope: Coordination of specialized zones including cold storage plants, outdoor pipe bridges, and chemical tank farms.
Chemical-Resistant Engineering: Implementation of corrosion-proof and leak-proof cleanroom environments tailored for aggressive chemical processes.
High-Capacity Output: Infrastructure built to support a 20+ ton annual API production scale.
Engineering Challenges & Solutions
Multidisciplinary Integration in EPC Mode: Managing a 40,000 sqm site involving labs, MEP, purification, and structural steel platforms required elite-level coordination. We utilized a unified project management team to synchronize various sub-disciplines, drastically reducing interference during overlapping construction phases.
Stringent Environment Control for API Synthesis: Chemical API production demands precise regulation of cleanliness, temperature, and pressure. We utilized a zonal management strategy to isolate core production areas from auxiliary zones, using high-grade, anti-corrosive materials to withstand solvent exposure while maintaining GxP compliance.
Complexity of Integrated Utility Systems: The project required the seamless connection of central chilling plants, outdoor pipe racks, and chemical storage tanks with the main workshops. We engineered a holistic utility network that ensures stable cooling and safe material transfer across the entire industrial footprint.
High-Stakes Chemical Storage & Piping: Designing and installing outdoor tank farms for diverse chemical solvents required rigorous safety standards. Our team optimized the layout of the outdoor pipe bridges to streamline energy and material flow between workshops, ensuring maximum operational efficiency.
Construction Content
Chemical API Production Suites: High-standard cleanrooms optimized for solvent handling and sterile API finishing.
R&D & Quality Control Laboratories: Specialized environments for pharmaceutical research and rigorous product testing.
Centralized Cold Storage & Chilling Plants: Large-scale refrigeration infrastructure for process cooling requirements.
Outdoor Infrastructure (Tank Farms & Pipe Racks): Total EPC of chemical storage facilities and inter-workshop utility bridges.
Heavy-Duty Mechanical & Equipment Installation: Precision positioning and integration of large-scale reactors and processing equipment.
Why This Project Defines AIPURE
“Mastering the complexity of industrial-scale pharmaceutical EPC.”
The Huilen Pharma project demonstrates AIPURE’s ability to lead mega-scale, multi-disciplinary engineering projects. By delivering 40,000 sqm of integrated production and utility infrastructure, we prove that our “Engineering Productization” logic applies perfectly to the most complex chemical and pharmaceutical manufacturing bases.
Project Conclusion
The high-standard delivery of the Huilen Pharma API base serves as a blueprint for large-scale pharmaceutical EPC excellence. Our integrated management ensured that all technical indicators met design requirements, enabling the successful launch of a 20-ton capacity production line. At AIPURE, we don’t just build workshops; we build the integrated industrial ecosystems that drive the pharmaceutical supply chain forward.
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Cleanroom Consulting
Cleanroom Design
Construction
Product Manufacturing
Commissioning
Operation & Maintain
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